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How Long Does Sildenafil Last?

Just like the amount of time required for sildenafil to start working, the amount of time sildenafil lasts can depend on several factors.

Most men notice the active effects of Viagra for approximately two to three hours. The drug can work for up to five hours in total, although it usually starts to become less effective and "wear off" after three hours.

Can Viagra Produce Permanent Effects?

No. Like all medications, Viagra has an active life and half life. The half life of sildenafil, which is the active ingredient in Viagra, is approximately four hours. This means that the active amount of Viagra in your bloodstream will reduce by approximately half with every four hours.

Beyond a certain point, Viagra will no longer be present in your bloodstream or tissue and it will produce no effects on your body.

Can External Factors Affect Sildenafil?

Yes. External factors, such as your diet or age, can have a significant effect on how well Viagra works and how long it remains active in your body:

Your diet can affect the amount of time sildenafil lasts for, as well as the amount of time required for sildenafil to start working. If you eat a large meal before taking the tablet, it can slow down the absorption process and delay the effects of Viagra.
Consuming alcohol can also affect sildenafil. Because alcohol has a negative effect on blood flow to the genitals, drinking wine, beer, spirits or other alcoholic beverages can make sildenafil less effective and increase the risk of side effects.

IMPORTANT SAFETY INFORMATION

Do not take Sildenafil (sildenafil citrate) if you:

take any medicines called nitrates, often prescribed for chest pain, or guanylate cyclase stimulators like Adempas (riociguat) for pulmonary hypertension. Your blood pressure could drop to an unsafe level
are allergic to sildenafil, as contained in Sildenafil and REVATIO, or any of the ingredients in Sildenafil
Discuss your health with your doctor to ensure that you are healthy enough for sex. If you experience chest pain, dizziness, or
nausea during sex, seek immediate medical help
Sildenafil can cause serious side effects. Rarely reported side effects include:

an erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, get medical help right away.
If it is not treated right away, priapism can permanently damage your penis
sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called
non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking Sildenafil and call your healthcare provider right away if you
have any sudden vision loss
sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness. If you have
these symptoms, stop taking Sildenafil and contact a doctor right away
Before you take Sildenafil, tell your healthcare provider if you:

have or have had heart problems such as a heart attack,
irregular heartbeat, angina, chest pain, narrowing of the aortic valve, or heart failure
have had heart surgery within the last 6 months
have pulmonary hypertension
have had a stroke
have low blood pressure, or high blood pressure that
is not controlled
have a deformed penis shape
have had an erection that lasted for more than 4 hours
have problems with your blood cells such as sickle cell
anemia, multiple myeloma, or leukemia
have retinitis pigmentosa, a rare genetic (runs in families)
eye disease
have ever had severe vision loss, including an eye problem
called NAION
have bleeding problems
have or have had stomach ulcers
have liver problems
have kidney problems or are having kidney dialysis have any other medical conditions
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins,
and herbal supplements.
Sildenafil may affect the way other medicines work, and other medicines may affect the way Sildenafil works, causing side effects.
Especially tell your healthcare provider if you take any of the following:
medicines called nitrates
medicines called guanylate cyclase stimulators such as Adempas (riociguat)
medicines called alpha-blockers such as Hytrin (terazosin
HCl), Flomax (tamsulosin HCl), Cardura (doxazosin
mesylate), Minipress (prazosin HCl), Uroxatral (alfuzosin HCl),
 Jalyn (dutasteride and tamsulosin HCl), or Rapaflo (silodosin).
Alpha-blockers are sometimes prescribed for prostate
problems or high blood pressure. In some patients, the use
of Sildenafil with alpha-blockers can lead to a drop in blood pressure or to fainting
medicines called HIV protease inhibitors, such as ritonavir (Norvir), indinavir sulfate (Crixivan), saquinavir (Fortovase or Invirase), or atazanavir sulfate (Reyataz)
some types of oral antifungal medicines, such as
 ketoconazole (Nizoral) and itraconazole (Sporanox)
some types of antibiotics, such as clarithromycin (Biaxin),
telithromycin (Ketek), or erythromycin
other medicines that treat high blood pressure
other medicines or treatments for ED
Sildenafil contains sildenafil, which is the same medicine found
in another drug called REVATIO. REVATIO is used to treat a
rare disease called pulmonary arterial hypertension (PAH).
 Sildenafil should not be used with REVATIO or with other PAH
treatments containing sildenafil or any other PDE5 inhibitors
(such as Adcirca tadalafil)
Sildenafil does not protect against sexually transmitted diseases, including HIV.
The most common side effects of Sildenafil: headache; flushing; upset stomach; abnormal vision, such as changes in color vision
(such as having a blue color tinge) and blurred vision; stuffy or runny nose; back pain; muscle pain; nausea; dizziness; rash.
H2 INDICATION
Sildenafil (sildenafil citrate) is prescription medicine used to treat erectile dysfunction (ED).
Sildenafil is not for women or children.

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